FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL
(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170
keywords: Antimicrobial activity, hydrazide, reflux, transition metal complex, synthesis
Complexes of isonicotinic acid hydrazide with Cu(II), Co(II) and Ni(II) have been prepared and characterized by analytical and physico-chemical techniques, such as elemental analysis, melting point and solubility studies, magnetic susceptibility and conductivity measurements, electronic and IR spectral studies. The infrared spectral studies revealed the bidentate nature of the Schiff base in the complexes; the ligand acting as neutral bidentate donor coordinating to the metal through the carbonyl O and the azomethine N. An octahedral geometry is suggestedfor all the complexes. The compounds were subjected to antimicrobial screening using serial broth dilution method and they show moderate antimicrobial activity.
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